Items Covered
- a.Viruses identified on the Australia Group (AG) "List of Human and Animal Pathogens and Toxins for Export Control," as follows:
- 1. African horse sickness virus;
- 2. African swine fever virus;
- 3. Andes virus;
- 4. Avian influenza (AI) viruses identified as having high pathogenicity (HP), as follows:
- 4.a. AI viruses that have an intravenous pathogenicity index (IVPI) in 6-week-old chickens greater than 1.2; or
- 4.b. AI viruses that cause at least 75% mortality in 4- to 8-week-old chickens infected intravenously.
- 5. Bluetongue virus;
- 6. Chapare virus;
- 7. Chikungunya virus;
- 8. Choclo virus;
- 9. Classical swine fever virus (Hog cholera virus);
- 10. Crimean-Congo hemorrhagic fever virus;
- 11. Dobrava-Belgrade virus;
- 12. Eastern equine encephalitis virus;
- 13. Ebolavirus (includes all members of the Ebolavirus genus);
- 14. Foot-and-mouth disease virus;
- 15. Goatpox virus;
- 16. Guanarito virus;
- 17. Hantaan virus;
- 18. Hendra virus (Equine morbillivirus);
- 19. Japanese encephalitis virus;
- 20. Junin virus;
- 21. Kyasanur Forest disease virus;
- 22. Laguna Negra virus;
- 23. Lassa virus;
- 24. Louping ill virus;
- 25. Lujo virus;
- 26. Lumpy skin disease virus;
- 27. Lymphocytic choriomeningitis virus;
- 28. Machupo virus;
- 29. Marburgvirus (includes all members of the Marburgvirus genus);
- 30. Middle East respiratory syndrome-related coronavirus (MERS-related coronavirus);
- 31. Monkeypox virus;
- 32. Murray Valley encephalitis virus;
- 33. Newcastle disease virus;
- 34. Nipah virus;
- 35. Omsk hemorrhagic fever virus;
- 36. Oropouche virus;
- 37. Peste-des-petits ruminants virus;
- 38. Porcine Teschovirus;
- 39. Powassan virus;
- 40. Rabies virus and all other members of the Lyssavirus genus;
- 41. Reconstructed 1918 influenza virus;
- 42. Rift Valley fever virus;
- 43. Rinderpest virus;
- 44. Rocio virus;
- 45. Sabia virus;
- 46. Seoul virus;
- 47. Severe acute respiratory syndrome-related coronavirus (SARS-related coronavirus);
- 48. Sheeppox virus;
- 49. Sin Nombre virus;
- 50. St. Louis encephalitis virus;
- 51. Suid herpesvirus 1 (Pseudorabies virus; Aujeszky's disease);
- 52. Swine vesicular disease virus;
- 53. Tick-borne encephalitis virus (Far Eastern subtype, formerly known as Russian Spring-Summer encephalitis virus-see 1C351.b.3 for Siberian subtype);
- 54. Variola virus;
- 55. Venezuelan equine encephalitis virus;
- 56. Vesicular stomatitis virus;
- 57. Western equine encephalitis virus; or
- 58. Yellow fever virus.
- b.Viruses identified on the APHIS/CDC "select agents" lists (see Related Controls paragraph #2 for this ECCN), but not identified on the Australia Group (AG) "List of Human and Animal Pathogens and Toxins for Export Control," as follows:
- 1. [Reserved];
- 2. [Reserved]; or
- 3. Tick-borne encephalitis virus (Siberian subtype, formerly West Siberian virus-see 1C351.a.53 for Far Eastern subtype).
- c.Bacteria identified on the Australia Group (AG) "List of Human and Animal Pathogens and Toxins for Export Control," as follows:
- 1. Bacillus anthracis;
- 2. Brucella abortus;
- 3. Brucella melitensis;
- 4. Brucella suis;
- 5. Burkholderia mallei (Pseudomonas mallei);
- 6. Burkholderia pseudomallei (Pseudomonas pseudomallei);
- 7. Chlamydia psittaci (Chlamydophila psittaci);
- 8. Clostriduim argentinense (formerly known as Clostridium botulinum Type G), botulinum neurotoxin producing strains;
- 9. Clostridium baratii, botulinum neurotoxin producing strains;
- 10. Clostridium botulinum;
- 11. Clostridium butyricum, botulinum neurotoxin producing strains;
- 12. Clostridium perfringens, epsilon toxin producing types;
- 13. Coxiella burnetii;
- 14. Francisella tularensis;
- 15. Mycoplasma capricolum subspecies capripneumoniae ("strain F38");
- 16. Mycoplasma mycoides subspecies mycoides SC (small colony) (a.k.a. contagious bovine pleuropneumonia);
- 17. Rickettsia prowazekii;
- 18. Salmonella enterica subspecies enterica serovar Typhi (Salmonella typhi);
- 19. Shiga toxin producing Escherichia coli (STEC) of serogroups O26, O45, O103, O104, O111, O121, O145, O157, and other shiga toxin producing serogroups;
- 20. Shigella dysenteriae;
- 21. Vibrio cholerae; or
- 22. Yersinia pestis.
- d."Toxins" identified on the Australia Group (AG) "List of Human and Animal Pathogens and Toxins for Export Control," as follows, or their subunits:
- 1. Abrin;
- 2. Aflatoxins;
- 3. Botulinum neurotoxins;
- 4. Brevetoxins;
- 5. Clostridium perfringens alpha, beta 1, beta 2, epsilon and iota toxins;
- 6. Conotoxins;
- 7. Diacetoxyscirpenol;
- 8. Gonyautoxins;
- 9. HT-2 toxin;
- 10. Microcystins (Cyanginosins);
- 11. Modeccin;
- 12. Neosaxitoxin (NEO);
- 13. Nodularins;
- 14. Palytoxin;
- 15. Ricin;
- 16. Saxitoxin;
- 17. Shiga toxins (shiga-like toxins, verotoxins, and verocytotoxins);
- 18. Staphylococcus aureus enterotoxins, hemolysin alpha toxin, and toxic shock syndrome toxin (formerly known as Staphylococcus enterotoxin F);
- 19. T-2 toxin;
- 20. Tetrodotoxin;
- 21. Viscumin (Viscum album lectin 1); or
- 22. Volkensin.
- e."Fungi", as follows:
- 1. Coccidioides immitis; or
- 2. Coccidioides posadasii.
Control Reasons Explained
This ECCN is controlled for the following reasons. Each reason maps to a column on the Commerce Country Chart, which determines whether a license is required for a given destination.
- ATAnti-Terrorism
- Basic anti-terrorism controls that apply to most items on the CCL. A license is required for exports to countries designated as state sponsors of terrorism.
Common Questions About 1C351
What does ECCN 1C351 cover?
ECCN 1C351 is an entry on the Commerce Control List (Materials). The List of Items Controlled below describes the products, software, or technology captured by this classification. Compare your item against those parameters when self-classifying.
How do license requirements work for this ECCN?
License need depends on the control reasons shown for this code (for example NS, RS, MT, AT), the destination country, and how your transaction maps against the Commerce Country Chart, de minimis, and other EAR provisions. This page is a research aid only. Confirm against the current rule text and your specific facts before exporting.
Where is the official text for this ECCN?
The legal text appears in Supplement No. 1 to part 774 of the Export Administration Regulations (15 CFR Part 774). Use the official BIS link on this page to open the current supplement entry for this ECCN.
What if my product matches more than one ECCN?
When several ECCNs appear to fit, the controlling entry is usually the one that is most specific to your item's form, function, or technical limits. Cross-references in the List of Items Controlled and related ECCNs listed on this page are common starting points for narrowing the choice.
How often should I re-check this classification?
The Commerce Control List changes when BIS publishes new or amended rules. Revisit the official entry when regulations update, when the product's technical parameters change, or when the destination, end-user, or end-use of a transaction changes.
What do the control reason codes mean?
Each control reason (NS, RS, MT, AT, etc.) maps to a column on the Commerce Country Chart in Supplement No. 1 to part 738 of the EAR. When a control reason applies to your ECCN and the destination country has an X in that column, a license is generally required unless an exception applies. See the Control Reasons Explained section on this page for details on each code.